The Clinicopathological Behavior and Pattern of Treatment of Inoperable Advanced Nonsmall Cell Lung Cancer Patients

Abstract: Lung cancer is leading cause of death due to malignancy. Non small cell lung cancer constitutes approximately 85% of all lung cancers. Despite advances in Lung cancer is leading cause of death due to malignancy. Non small cell lung cancer constitutes approximately 85% of all lung cancers. Despite advances in early detection of non small cell lung cancer, about 75%-80% patients with locally advanced or metastatic disease (Stage III & IV) and carries poor prognosis. Majority of these patients are not candidate for a surgical treatment. Treatments such as chemotherapy and radiotherapy or combined modality have been tried in these patients in term of improve survival and quality of life. Material and Methods: A retrospective analysis of 120 patients with advanced stage NSCLC was undertaken. The clinicopathological behavior observed and pattern of treatment they received such as radical and palliative treatment in form of radiotherapy and chemotherapy evaluated. Results: Median age of presentation was 58 years, more common in male patients (84%) and smokers. Of total 120 patients only 39 (33%) received radical treatment, palliative treatment was received by 61 (51%) of cases. Whereas 17% patients were not received any treatment. Conclusions: Combination chemotherapy and radiotherapy improve symptoms and quality of life.